Blar i forfatter "Nordheim, Espen"

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    • Chronic kidney disease in patients with diabetes mellitus 

      Nordheim, Espen; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)
      Chronic kidney disease is a common complication and concomitant condition of diabetes mellitus. The treatment of patients with diabetes and chronic kidney disease, including intensive control of blood sugar and blood pressure, has been very similar for type 1 and type 2 diabetes patients. New therapeutic targets have shown promising results and may lead to more specific treatment options for patients ...

    • Criteria for prediabetes and posttransplant diabetes mellitus after kidney transplantation: A 2-year diagnostic accuracy study of participants from a randomized controlled trial 

      Kurnikowski, Amelie; Nordheim, Espen; Schwaiger, Elisabeth; Krenn, Simon; Harreiter, Jürgen; Kautzky-Willer, Alexandra; Leutner, Michael; Werzowa, Johannes; Tura, Andrea; Budde, Klemens; Eller, Kathrin; Pascual, Julio; Krebs, Michael; Jenssen, Trond Geir; Hecking, Manfred (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Posttransplant diabetes mellitus (PTDM) and prediabetes (impaired glucose tolerance [IGT] and impaired fasting glucose [IFG]) are associated with cardiovascular events. We assessed the diagnostic performance of fasting plasma glucose (FPG) and HbA<sub>1c</sub> as alternatives to oral glucose tolerance test (OGTT)-derived 2-hour plasma glucose (2hPG) using sensitivity and specificity in 263 kidney ...

    • Endothelial function after pancreas transplantation - A single-center observational study 

      Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...

    • Outcomes in pancreas transplantation with exocrine drainage through a duodenoduodenostomy versus duodenojejunostomy 

      Lindahl, Jørn Petter Hanto; Horneland, Rune; Nordheim, Espen; Hartmann, Anders; Aandahl, Einar Martin; Grzyb, Krzysztof; Haugaa, Håkon; Kjøsen, Gisle; Åsberg, Anders; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel, 2017-08-23)
      Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access for biopsies. This study assessed safety profiles with DD versus DJ procedures and clinical outcomes with the DD technique in pancreas transplantation. DD patients (n = 117; 62 ...

    • Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach 

      Nordheim, Espen; Lindahl, Jørn Petter Hanto; Carlsen, Rasmus Kirkeskov; Åsberg, Anders; Birkeland, Kåre I.; Horneland, Rune; Boye, Birgitte; Scholz, Hanne; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02)
      Objective - β-cell replacement therapy (βCRT), including pancreas transplantation alone (PTA) and islet transplantation (ITX), is a treatment option for selected type 1 diabetes patients. All potential candidates for βCRT in Norway are referred to one national transplant centre for evaluation before any pre-transplant workup is started. This evaluation was performed by a transplant nephrologist alone ...

    • Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation 

      Ussif, Mohammed Al-Amin; Åsberg, Anders; Strøm Halden, Thea Anine; Nordheim, Espen; Hartmann, Anders; Jenssen, Trond Geir (Journal article; Peer reviewed, 2019-01-10)
      <b>Background</b><br> The use of HbA1c ≥6.5% for diagnosis of diabetes has been challenged for post-transplantation diabetes mellitus (PTDM) also known as new onset diabetes after transplantation (NODAT) due to a low sensitivity early after renal transplantation. PTDM diagnosed with an oral glucose tolerance test (OGTT) is highly predictable for long-term patient mortality. HbA1c was introduced for ...